ACETAMINOPHEN, SALICYLATES & NONSTEROIDAL ANTI INFLAMMATORY DRUGS Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N acetyl parabenzoquinone imine and its antidote, N acetyl l cysteine Scientific Reports NAPQI Wikipedia Simplified scheme of APAP metabolism, leading to the formation of NAPQI Download Scientific Diagram Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting, Solved The stepwise mechanism below shows how glutathione Chegg.com